Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

نویسندگان

  • Camila Spereta Bertanha
  • Ana Helena Januário
  • Tavane Aparecida Alvarenga
  • Letícia Pereira Pimenta
  • Márcio Luis Andrade e Silva
  • Wilson Roberto Cunha
  • Patrícia Mendonça Pauletti
چکیده

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Natural Products from Antarctic Colonial Ascidians of the Genera Aplidium and Synoicum: Variability and Defensive Role

Ascidians have developed multiple defensive strategies mostly related to physical, nutritional or chemical properties of the tunic. One of such is chemical defense based on secondary metabolites. We analyzed a series of colonial Antarctic ascidians from deep-water collections belonging to the genera Aplidium and Synoicum to evaluate the incidence of organic deterrents and their variability. The...

متن کامل

Anti-predatory chemical defenses of ascidians: secondary metabolites or inorganic acids?

Both secondary metabolites and inorganic acids have been hypothesized to protect adult ascidians from predation, raising the possibility of alternative defensive strategies in these sessile, soft-bodied, benthic invertebrates. The objective of this investigation was to determine if ascidian species from the Western Atlantic have these chemical defenses against fish predators, and if so, to dete...

متن کامل

Taxonomic and Metabolite Diversity of Actinomycetes Associated with Three Australian Ascidians

Actinomycetes are known to be the most prolific producers of biologically active metabolites. Here, we investigated the host species-specificity and the related secondary metabolites of actinomycetes that are associated with three different Australian ascidians, namely Symplegma rubra, Aplidium solidum, and Polyclinum vasculosum. Results indicated that while isolates from the genera Streptomyce...

متن کامل

Identification of Ascidians (Tunicata: Ascidiacea) around Larak Island in the Persian Gulf

Despite the variety of marine organisms recorded from the Persian Gulf, acidians located along the Persian Gulf have not received much attention. We collected Ascidian samples from four sites along  Larak Island (Persian Gulf) using Scuba diving and snorkeling at a depth that ranged from 5-15 m. Taxonomic identification was carried out by authoritative keys and texts. We found 4 species that be...

متن کامل

A review on toxicological properties of thymoquinone a natural broad spectrum ingredient

Background and objectives: Nigella sativa is a delicate floral vegetable belonging to Ranunculaceae family. Thymoquinone (TQ) is the dominant active component in Nigella sativa seed oil which has a variety of pharmacological properties such as antioxidant, anticancer, anti-inflammatory and analgesic activities. However, TQ is a quinone derivative, which may le...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2014